アブストラクト | BACKGROUND: The purpose of the present study was to investigate 30-day postoperative outcomes after lower extremity amputation in patients with diabetes mellitus (DM) alone, peripheral artery disease (PAD) alone, or both. METHODS: Eight thousand five hundred sixty-five patients with DM alone (n = 2,700), PAD alone (n = 2,919), and both (n = 2,946) who had above-knee amputation or below-knee amputation during 2007 to 2012 from the Japanese Diagnosis Procedure Combination inpatient database were retrospectively analyzed. RESULTS: Overall 30-day mortality was 6.4% (5.1%, 8.5%, and 5.6% in DM alone, PAD alone and both group, respectively). Multivariable regression analysis showed no significant differences in 30-day mortality or overall postoperative complication rates among the 3 groups. Patients with both PAD and DM had a significantly higher proportion of cardiac events than those with DM alone (6.9% vs 3.0%; odds ratio = 2.27; 95% confidence interval = 1.73 to 2.98). CONCLUSIONS: Patients with both DM and PAD were more likely to have postoperative cardiac events. |
ジャーナル名 | American journal of surgery |
投稿日 | 2016/2/3 |
投稿者 | Yamada, Keiko; Yasunaga, Hideo; Kadono, Yuho; Chikuda, Hirotaka; Ogata, Toru; Horiguchi, Hiromasa; Tanaka, Sakae |
組織名 | Department of Clinical Epidemiology and Health Economics, School of Public;Health, The University of Tokyo, Tokyo, Japan.;Health, The University of Tokyo, Tokyo, Japan. Electronic address:;yasunagah-tky@umin.ac.jp.;Faculty of Medicine, Department of Sensory & Motor System Medicine, The;University of Tokyo, Tokyo, Japan.;Department of Rehabilitation for Movement Functions, National Rehabilitation;Center for Persons with Disabilities, Research Institute, Saitama, Japan.;Department of Clinical Data Management and Research, Clinical Research Center,;National Hospital Organization Headquarters, Tokyo, Japan. |
Pubmed リンク | https://www.ncbi.nlm.nih.gov/pubmed/26830717/ |