| アブストラクト | INTRODUCTION: Type 2 diabetes is associated with an increased risk of fragility fractures, even in individuals with normal or high bone mineral density. However, the impact of type 2 diabetes on postoperative outcomes after hip fracture surgery in elderly Japanese patients remains unclear. This study evaluated the association between type 2 diabetes and postoperative complications, including in-hospital mortality, using a nationwide database in Japan. MATERIALS AND METHODS: A retrospective cohort study was conducted using the Diagnosis Procedure Combination (DPC) database from April 2016 to March 2022. Patients aged >/= 65 years who underwent hip fracture surgery were included. Propensity score matching (1:1) was performed to adjust for confounders. Logistic regression analyses were used to assess associations between type 2 diabetes and outcomes. RESULTS: Of the 474,293 eligible patients included in this study, 18.5% were identified as having comorbid type 2 diabetes. Following 1:1 propensity score matching, the final analytic cohorts each comprised 83,283 patients. Although statistically significant, the presence of type 2 diabetes was associated with only modest increases in the risks of postoperative myocardial infarction (risk difference [RD]: 0.0007), cognitive dysfunction (RD: 0.0029), and in-hospital mortality (RD: 0.0045), with all comparisons yielding p-values of less than 0.0001. Additionally, the length of hospital stay was longer among patients with type 2 diabetes. CONCLUSIONS: Although the absolute risk differences were small, type 2 diabetes remains an independent risk factor for adverse postoperative outcomes following hip fracture surgery in elderly Japanese patients. Tailored perioperative strategies may help optimize outcomes in this vulnerable population. |
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| ジャーナル名 | Journal of bone and mineral metabolism |
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| Pubmed追加日 | 2025/7/2 |
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| 投稿者 | Mori, Yu; Tarasawa, Kunio; Tanaka, Hidetatsu; Mori, Naoko; Fushimi, Kiyohide; Aizawa, Toshimi; Fujimori, Kenji |
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| 組織名 | Department of Orthopaedic Surgery, Tohoku University Graduate School of Medicine,;1-1 Seiryo-machi, Aoba-Ku, Sendai, Miyagi, 980-8574, Japan.;yu.mori.c4@tohoku.ac.jp.;Department of Health Administration and Policy, Tohoku University Graduate School;of Medicine, 2-1 Seiryo-machi, Aoba-Ku, Sendai, Miyagi, 980-8574, Japan.;Department of Radiology, Akita University Graduate School of Medicine, 1-1-1;Hondo, Akita, Akita, 010-8543, Japan.;Department of Health Policy and Informatics, Institute of Science Tokyo, 1-5-45;Yushima, Bunkyo-Ku, Tokyo, 113-8519, Japan. |
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| Pubmed リンク | https://www.ncbi.nlm.nih.gov/pubmed/40593307/ |
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