Prevalence of myocardial injury requiring percutaneous coronary intervention after acute carbon monoxide poisoning.
OBJECTIVE: More than one-third of patients with moderate to severe acute carbon monoxide (CO) poisoning had myocardial injury. However, the ratio of acute CO patients necessitating percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG) remains unknown. This study aimed to examine the prevalence of myocardial injury requiring PCI or CABG in patients with CO poisoning.
METHODS: This was a nationwide retrospective cohort study, using the Japanese Diagnosis Procedure Combination inpatient database focusing on the period between 2010 and 2017. We extracted data on patients diagnosed with CO poisoning and determined the prevalence of cases presenting with myocardial injury requiring PCI or CABG.
RESULTS: We identified 9091 eligible patients. Within this patient pool, eight patients underwent PCI within 2 days of admission. No patients required CABG. The prevalence of subsequent PCI was 0.09% (8/9091). The patients who required PCI had a significantly higher median age than those who did not (75 vs. 52 years of age, respectively). Patients requiring PCI were older and were more likely to have underlying comorbidities such as hypertension and diabetes mellitus.
CONCLUSION: The present study reported a low prevalence of myocardial injury requiring PCI in acute CO poisoning patients. Although myocardial injury due to coronary artery occlusion would be a very rare presentation in the setting of acute CO poisoning, coronary occlusion should be taken into consideration for elderly patients and/or patients who have coronary risk factors.
|ジャーナル名||European journal of emergency medicine : official journal of the European Society for Emergency Medicine|
|投稿者||Nakajima, Mikio; Aso, Shotaro; Matsui, Hiroki; Kaszynski, Richard H; Fushimi, Kiyohide; Yamaguchi, Yoshihiro; Yasunaga, Hideo|
|組織名||Emergency and Critical Care Center, Tokyo Metropolitan Hiroo Hospital,;Shibuya-ku.;Department of Clinical Epidemiology and Health Economics, School of Public;Health, The University of Tokyo, Bunkyo-ku.;Department of Trauma and Critical Care Medicine, School of Medicine, Kyorin;University, Mitaka-shi.;Department of Health Policy and Informatics, Tokyo Medical and Dental University;Graduate School of Medicine, Bunkyo-ku, Tokyo, Japan.|