Pristinamycin-induced arthralgia and myalgia: Analysis of the French Pharmacovigilance Database.
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アブストラクト INTRODUCTION:Pristinamycin is an antibiotic of the streptogramin family; few adverse effects of this drug are reported, only cutaneous and digestive ones. Arthralgia and myalgia may however be observed although not mentioned in the summary of product characteristics.OBJECTIVE:Description and analysis of cases of pristinamycin-induced arthralgia and/or myalgia registered in the French database of pharmacovigilance.METHOD:We carried out a targeted search of the database, selecting case patients presenting with arthralgia and muscle pain and excluding those associated with sensitivities or allergies to pristinamycin.RESULTS:We retrieved 15 case patients of pristinamycin-induced arthralgia and myalgia. Pristinamycin was the only potentially incriminated drug for seven case patients.CONCLUSION:Although not serious, this adverse effect deserves to be better known by physicians to optimize therapeutic management.ジャーナル名 Medecine et maladies infectieuses 投稿日 2017/11/8 投稿者 Denis Prevot, M; Thillard, E M; Walther, J; Veyrac, G; Laroche, M L; Gautier, S; Auffret, M 組織名 Centre regional de pharmacovigilance de Lille, faculte de medecine, CHRU de;Lille, 1, place de Verdun, 59037 Lille cedex, France. Electronic address:;man.prevot@gmail.com.;evemarie.thillard@gmail.com.;Pharmacie centrale, CHRU de Lille, 2, avenue Oscar-Lambret, 59037 Lille cedex,;France. Electronic address: julia.walther@chru-lille.fr.;Service de pharmacologie clinique, centre regional de pharmacovigilance de;Nantes, CHU de Nantes, 9, quai Moncousu, 44093 Nantes cedex, France. Electronic;address: gwenaelle.veyrac@chu-nantes.fr.;Service de pharmacologie, toxicologie et pharmacovigilance, centre regional de;pharmacovigilance, de pharmacoepidemiologie et d'information sur les medicaments,;CHU de Limoges, batiment CBRS, 2(e) etage, 2, avenue Martin-Luther-King, 87042;Limoges cedex, France. Electronic address: Marie-Laure.Laroche@chu-limoges.fr.;sophie.gautier@chru-lille.fr.;marine.auffret@chru-lille.fr. Pubmed リンク https://www.ncbi.nlm.nih.gov/pubmed/29110913/ -
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