Pulmonary fibrosis and lung cancer: an analysis of the Clinical Practice Research Datalink linked to the National Cancer Registration Dataset.

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Pulmonary fibrosis and lung cancer: an analysis of the Clinical Practice Research Datalink linked to the National Cancer Registration Dataset.

アブストラクト	We quantified the proportion of diagnoses of pulmonary fibrosis (PF) among 25 136 people with lung cancer and 250 583 matched controls and compared the natural history of lung cancer in people with and without PF. Diagnoses of PF were more common in people with lung cancer than those without (1.5% vs 0.8%, OR 1.97; 95% CI 1.77 to 2.21). Within people with PF, squamous cell carcinoma was more (22.9% vs 19.1%), and adenocarcinoma was less common (18.0% vs 21.3%). People with PF were less likely to have stage 4 disease at diagnosis (OR 0.43, 95% CI 0.28 to 0.65) but their survival was worse.
ジャーナル名	Thorax
Pubmed追加日	2024/9/11
投稿者	Gonnelli, Francesca; Kaur, Jaspreet; Bonifazi, Martina; Baldwin, David; O'Dowd, Emma; Hubbard, Richard
組織名	Translational Medical Sciences, University of Nottingham, Nottingham, UK;francesca.gonnelli@nottingham.ac.uk.;Biomedical Sciences and Public Health, Polytechnic University of Marche, Ancona,;Italy.;Translational Medical Sciences, University of Nottingham, Nottingham, UK.;Interstitial Lung Diseases, Pleural Diseases and Bronchiectasis Unit, Ospedali;Riuniti Ancona Umberto I-G.M. Lancisi-G. Salesi, Ancona, Italy.;Respiratory Medicine, Nottingham University Hospitals, Nottingham, UK.;University of Nottingham, Nottingham, UK.
Pubmed リンク	https://www.ncbi.nlm.nih.gov/pubmed/39256044/