| アブストラクト | Background: Respiratory Syncytial Virus is a predominant source of morbidity and mortality, particularly among babies, the elderly, and immunocompromised patients. Recent developments in RSV vaccines, approved by the FDA for high-risk groups, have highlighted the necessity for post-marketing surveillance to evaluate their real-world safety and efficacy. Method: This study utilized data from the Vaccine Adverse Event Reporting System (VAERS) covering RSV vaccine administration between 2023 and May 2025. The VAERS database reported data on vaccine types, including Arexvy((R)), Abrysvo((R)), and mRESVIA((R)) was analyzed for adverse events and vaccination errors. The demographic information, vaccination trends, and hospitalizations post-vaccination among the vaccinated individuals were accessed. Results: The analysis revealed that the most common adverse events were mild, such as injection site pain, erythema, fatigue, and extremity pain. The data also showed a gradual increase in hospitalization rates from 4.8% in 2023 to 7.5% in 2025. Vaccination errors, including inappropriate administration during pregnancy and excess doses, were also observed. A notable trend was the growing proportion of patients who experienced no adverse events, with the highest rate of symptom-free reports seen in 2025 (25.9%). Conclusions: RSV vaccines demonstrate a generally acceptable safety profile based on post-marketing surveillance data. However, the observed increase in hospitalization rates, vaccination errors, and pregnancy-related outcomes warrants continued active surveillance and cautious interpretation. |
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| ジャーナル名 | Diseases (Basel, Switzerland) |
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| Pubmed追加日 | 2026/1/27 |
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| 投稿者 | Alshammari, Thamir M; Alshammari, Mohammed K; Alosaimi, Hind M |
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| 組織名 | Department of Clinical Practice, College of Pharmacy, Jazan University, Jazan;45142, Saudi Arabia.;Pharmacy Practice Research Unit, College of Pharmacy, Jazan University, Jazan;Department of Pharmaceutical Care Administration, Research and Studies Unit at;Rafha General Hospital, Northern Border Healthcare Cluster, Rafha 76312, Saudi;Arabia.;Department of Pharmacy Services Administration, King Fahad Medical City, Riyadh;Second Health Cluster, Riyadh 12211, Saudi Arabia. |
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| Pubmed リンク | https://www.ncbi.nlm.nih.gov/pubmed/41590244/ |
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