| アブストラクト | CONTEXT: Trends in incidence of Polycystic Ovary Syndrome (PCOS) and effects on health resource utilization are unclear. OBJECTIVES: To describe trends in prevalence and incidence of PCOS in the United Kingdom. To establish healthcare resource use and associated costs. DESIGN: Data were extracted from the Clinical Practice Research Datalink Aurum and Hospital Episode Statistics databases. Point prevalence and incidence were calculated (2004-2020). Patients with PCOS were matched to controls (1:1) by age, body mass index and primary care practice. Primary care contacts were assigned an average cost and prescription items assigned a net ingredient cost. Inpatient admissions and outpatient consultations were processed into Healthcare Resource Groups and costed to the National Tariff. RESULTS: PCOS incidence increased from 1.22 per 1000 person years in 2004 to 1.77 (2012) and 2.20 (2019). Point prevalence increased from 1.02% (2004) to 2.2% (2012) and 3.5% (2020), and was highest in Asians. Mean contacts per person year (ppy) for patients with PCOS versus controls were 0.48 vs 0.29 for inpatients (p<0.001), 3.81 vs 2.15 for outpatients (p<0.001) and 6.43 vs 4.68 (p<0.001) for primary care. Mean healthcare costs (ppy) were pound837 vs pound493 (p<0.001) for inpatients, pound444 vs pound253 (p<0.001) for outpatients, pound157 vs pound112 for primary care and pound109 vs pound83 (p<0.001) for primary care prescriptions. Total health care contacts ppy were 10.72 vs 7.11 (p<0.001) and total associated costs pound1,546 vs pound940 (p<0.001). CONCLUSION: The incidence of PCOS has risen significantly. Health resource utilization and costs of PCOS are significantly greater than controls. |
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| ジャーナル名 | The Journal of clinical endocrinology and metabolism |
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| 投稿日 | 2024/7/26 |
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| 投稿者 | Berni, Thomas R; Morgan, Christopher L; Rees, D Aled |
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| 組織名 | Human Data Sciences, 24 Wordsworth Avenue, Cardiff, CF24 3FR, UK.;Neuroscience and Mental Health Innovation Institute, School of Medicine, Cardiff;University, Cardiff, CF24 4HQ, UK. |
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| Pubmed リンク | https://www.ncbi.nlm.nih.gov/pubmed/39049776/ |
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