| アブストラクト | STUDY DESIGN: A retrospective comparative study. OBJECTIVE: This study aimed to investigate factors associated with postoperative unfavorable ambulatory status following surgery for metastatic spinal tumors using a nationwide in-hospital database. SUMMARY OF BACKGROUND DATA: Surgical treatment for metastatic spinal tumors can improve the ambulatory status and quality of life. However, some patients fail to regain the ability to walk, thereby resulting in poor quality of life. No large-scale study has previously evaluated factors associated with postoperative poor ambulatory status in this clinical context. MATERIALS AND METHODS: The Diagnosis Procedure Combination database from 2018 to 2019 was used to extract data from patients who underwent surgical procedures for spinal metastasis. Postoperative unfavorable ambulatory status was defined as (1) nonambulatory at discharge or (2) a decreased mobility score of the Barthel Index between admission and discharge. Multivariable logistic regression was used to evaluate factors associated with postoperative unfavorable ambulatory status while adjusting for confounders. RESULTS: This study analyzed 1786 eligible patients. Of whom, 1061 (59%) patients were ambulatory on admission and 1249 (70%) on discharge. Postoperative unfavorable ambulatory status was observed in 597 (33%) patients, with a significantly lower rate of discharge to home (41%/81%, P <0.001) and a longer postoperative hospital stay (46.2 days/31.4 days, P <0.001). Multivariable regression analysis revealed male sex [odds ratio (OR): 1.43, P =0.002], laminectomy without fusion (OR: 1.55, P =0.034), Charlson Comorbidity Index of >/=7 (OR: 1.37, P =0.014), and preoperative nonambulatory status (OR: 6.61, P <0.001) as factors associated with postoperative unfavorable ambulatory status. CONCLUSIONS: Our large-scale database analysis revealed that 33% of patients experienced unfavorable ambulatory status following spinal metastasis surgery. Laminectomy without fusion and preoperative nonambulatory status were among several factors influencing the prospect of unfavorable ambulatory status following surgery. |
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| ジャーナル名 | Spine |
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| 投稿日 | 2023/5/18 |
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| 投稿者 | Yamada, Kentaro; Yoshii, Toshitaka; Toba, Mikayo; Kudo, Atsushi; Egawa, Satoru; Matsukura, Yu; Hirai, Takashi; Inose, Hiroyuki; Fushimi, Kiyohide; Okawa, Atsushi |
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| 組織名 | Department of Orthopaedic and Trauma Research, Tokyo Medical and Dental;University, Tokyo, Japan.;Department of Orthopaedics, Tokyo Medical and Dental University, Tokyo, Japan.;Department of Quality Management Center, Tokyo Medical and Dental University;Hospital, Tokyo, Japan.;Department of Hepato-Biliary-Pancreatic Surgery, Tokyo Medical and Dental;Department of Health Policy and Informatics Section, Tokyo Medical and Dental |
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| Pubmed リンク | https://www.ncbi.nlm.nih.gov/pubmed/37199435/ |
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