| アブストラクト | BACKGROUND: We aimed to evaluate the short-term outcomes of pancreatoduodenectomy (PD) in older individuals. METHODS: Data from the Japanese Diagnosis Procedure Combination database on 62 275 patients who underwent PD from 1 April 2012 to 31 March 2020 were analyzed. Patients were divided into five age groups: <70, 70-74, 75-79, 80-84, and >/=85 years. The associations between postoperative outcomes and age were investigated using multilevel analysis. The mean differences in length of hospital stay and cost were also compared. RESULTS: The rate of PD in older individuals increased annually. Compared with the youngest age group (< 70 years), the incidence rate ratios for in-hospital mortality were 1.52 (95% confidence interval [CI]: 1.30-1.76), 2.07 (1.82-2.37), 2.29 (1.94-2.71), and 2.92 (2.20-3.87) in the 70-74, 75-79, 80-84, and >/= 85-year-old age groups, respectively (all p < .001). Postoperative complications, length of postoperative hospital stay, and cost increased significantly with increasing age. CONCLUSIONS: These real-world data emphasize the higher levels of morbidity, mortality, and cost in older patients. Careful attention should be paid when considering the indication for PD in older individuals. |
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| ジャーナル名 | Journal of hepato-biliary-pancreatic sciences |
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| 投稿日 | 2023/11/30 |
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| 投稿者 | Mori, Yasuhisa; Okawara, Makoto; Shibao, Kazunori; Kohi, Shiro; Tamura, Toshihisa; Sato, Norihiro; Fujino, Yoshihisa; Fushimi, Kiyohide; Matsuda, Shinya; Hirata, Keiji |
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| 組織名 | Department of Surgery 1, School of Medicine, University of Occupational and;Environmental Health, Kitakyushu, Japan.;Department of Environmental Epidemiology, Institute of Industrial Ecological;Sciences, University of Occupational and Environmental Health, Kitakyushu, Japan.;Department of Health Policy and Informatics, Tokyo Medical and Dental University;Graduate School of Medical and Dental Sciences, Tokyo, Japan.;Department of Preventive Medicine and Community Health, School of Medicine,;University of Occupational and Environmental Health, Kitakyushu, Japan. |
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| Pubmed リンク | https://www.ncbi.nlm.nih.gov/pubmed/38031900/ |
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