| アブストラクト | The high incidence of error reports received by the US Food and Drug Administration (FDA) involving 2-component vaccines led to collaboration between the United States Pharmacopeia (USP) and the Institute for Safe Medication Practices (ISMP). This collaborating group sought to further understand errors associated with all 2-component vaccines (i.e. vaccine components provided by the manufacturer in physically separate containers) and to provide safe practice strategies for storing, preparing, dispensing, and administering these vaccines as intended. Fourteen available 2-component vaccines were identified. The ISMP National Vaccine Errors Reporting Program (VERP) and the FDA Vaccine Adverse Event Reporting System (VAERS) were searched from the initiation of each respective reporting system through December 31, 2019. The three vaccines with the most reported reconstitution errors in the VERP and VAERS are Menveo((R)) (meningococcal), Pentacel((R)) (DTaP, Polio, Haemophilus influenzae type b), and ActHIB((R)) [H. influenzae type b (Hib)]. Manufacturers should design labeling and packaging of vaccines to provide ease of storage and fail-safe preparation to prevent 2-component vaccine errors. Implementing risk reduction strategies, such as training healthcare professionals and affixing storage bin labels, remind healthcare professionals to mix the 2-components and facilitate appropriate administration. |
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| 投稿日 | 2020/11/6 |
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| 投稿者 | Samad, Farzana; Burton, Samantha J; Kwan, Diana; Porter, Noah; Smetzer, Judy; Cohen, Michael R; Tuttle, Jeanne; Baker, Danial; Doherty, Dennis E |
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| ジャーナル名 | Pharmaceutical medicine |
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| 組織名 | Institute for Safe Medication Practices, Horsham, PA, USA.;United States Pharmacopeia, Rockville, MD, USA. dck@usp.org.;United States Pharmacopeia, Rockville, MD, USA.;Department of Veterans Affairs, Pharmacy Benefits Management Services, Washington;DC, USA.;College of Pharmacy and Pharmaceutical Sciences, Washington State University,;Spokane, WA, USA.;Division of Pulmonary, Critical Care, and Sleep Medicine, University of Kentucky,;College of Medicine and Chandler Medical Center, Lexington, KY, USA. |
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| Pubmed リンク | https://www.ncbi.nlm.nih.gov/pubmed/33151497/ |
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