| アブストラクト | INTRODUCTION: Atopic dermatitis (AD) is a chronic inflammatory skin condition requiring long-term management to maintain remission and prevent relapse. Appropriate use of topical anti-inflammatory medications is an important factor in improving symptoms in patients with AD. This study aimed to investigate the treatment methods for maintaining remission and application of anti-inflammatory topical therapy. METHODS: This observational study was conducted in October 2022, using medical claims data from DeSC Healthcare Inc., linked with survey data collected from users of kencom(R), a health promotion application. Eligible patients were adults aged >/= 19 years with a confirmed AD diagnosis and prescription history. The survey evaluated (1) the actual treatment situation during the remission maintenance phase; and (2) instructions, actual status and adherence for application of anti-inflammatory topical therapy. RESULTS: A total of 626 patients who answered the kencom(R) survey and met eligibility criteria were included. Of these, 42.3% were instructed to stop medication once eczema improved, while 34.2% were instructed to continue during remission. Regarding instructions for the amount applied, the most common response was "No specific instructions" (44.2%), followed by "Fingertip-unit (FTU)" (27.2%). In actual practice, "FTU" was the most common amount (42.2%). Regarding application area, the most frequent instruction and actual practice were "Apply only to areas with eczema with remaining inflammation" at 52.6% and 62.5%, respectively, followed by "Apply not only to the eczema or remaining inflamed areas but also the surrounding areas" at 24.0% and 37.2%. Regarding the application method, "Apply thinly" was the most common instruction and actual practice at 32.7% and 48.4%, respectively. Treatment adherence rates were generally high, at over 60%. CONCLUSION: Guidance from healthcare professionals has a crucial role in the proper use of topical therapies for AD. It is essential to ensure that topical medications are used properly to help patients achieve their treatment goals. |
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| 投稿者 | Murota, Hiroyuki; Noto, Shinichi; Matsukawa, Miyuki; Konishi, Yasuhito; Michikami, Daisaku; Toda, Rikiya; Nakahara, Takeshi |
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| 組織名 | Department of Dermatology, Graduate School of Biomedical Sciences, Nagasaki;University, 1-7-1 Sakamoto, Nagasaki City, Nagasaki, 852-8523, Japan.;Department of Rehabilitation, Niigata University of Health and Welfare, 1398;Shimamicho, Kita-Ku, Niigata City, Niigata, 950-3198, Japan.;Medical Affairs, Otsuka Pharmaceutical Co., Ltd., 3-2-27 Otedori, Chuo-Ku, Osaka,;540-0021, Japan. Matsukawa.Miyuki@otsuka.jp.;Medical Affairs, Otsuka Pharmaceutical Co., Ltd., Shinagawa Grand Central Tower,;2-16-4 Konan, Minato-Ku, Tokyo, 108-8241, Japan.;Department of Dermatology, Graduate School of Medical Sciences, Kyushu;University, 3-1-1 Maidashi, Higashi-Ku, Fukuoka City, Fukuoka, 812-8582, Japan. |
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