| アブストラクト | Spina bifida is a congenital neural tube defect that results in abnormal development of the spine and central nervous system. Infants born with this condition face a range of physical disabilities and associated complications. Although the global burden has declined in recent decades due to folic acid fortification and prenatal screening, spina bifida remains a significant public health challenge in many low- and middle-income countries (LMICs), particularly in sub-Saharan Africa. This research aimed to comprehensively assess the current epidemiological trends, clinical management practices, and socioeconomic impacts of spina bifida across African LMICs. Through a systematic analytical search of published literature from major medical databases covering the years 2000-2023, relevant data were extracted on the prevalence, risk factors, clinical presentations, treatment modalities, outcomes, and contextual barriers faced in preventing and caring for spina bifida in these settings. The findings were analyzed and synthesized to provide an overview of the contemporary landscape. The findings highlight the need for collaborative efforts between governments, healthcare providers, nongovernmental organizations, and international stakeholders to address the multifaceted challenges posed by spina bifida in LMICs, particularly within the African continent, and to promote equitable access to comprehensive care and support for affected individuals and their families. |
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| 投稿者 | Okon, Inibehe Ime; Temitope, Agbeniga Elijah; Ogundele, Ibukunolu Olufemi; Akpan, Usoro; Mbong, Emem Okon; Kasimieh, Omar; Chaurasia, Bipin; James, Emmanuel; Gbadebo, Elkan; Precious, Fadele Kehinde; Jader, Arwa; Okesanya, Olalekan John; Karmani, Vishal; Erhayanmen, Michael; Lucero-Prisno Iii, Don Eliseo |
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| 組織名 | Department of Neurosurgery, Dell Medical School, University of Texas at Austin,;Texas, United States; Benjamin S. Carson (Snr) College of Health and Medical;Sciences, Babcock University, IIishan-Remo, Ogun State 121003, Nigeria.;Electronic address: inibeheokon3@gmail.com.;Benjamin S. Carson (Snr) College of Health and Medical Sciences, Babcock;University, IIishan-Remo, Ogun State 121003, Nigeria. Electronic address:;agbenigaelijah21@gmail.com.;Department of Surgery, Olabisi Onabanjo University Teaching Hospital, Sagamu,;Ogun State, Nigeria. Electronic address: ogundeleibk@gmail.com.;Department of Public Health, Warwick Medical School, University of Warwick,;United Kingdom. Electronic address: usoroakpan33@gmail.com.;Department of Biological Sciences, Ritman University, Ikot Ekpene, Nigeria.;Electronic address: Mbongemem@yahoo.com.;College of Medicine, University of the East Ramon Magsaysay Memorial Medical;Center, Manilla, Philippines. Electronic address: omar.kasimieh@gmail.com.;Department of Neurosurgery, Neurosurgery Clinic, Birgunj, Nepal. Electronic;address: trozexa@gmail.com.;Department of Medicine and Surgery, University of Benin, Benin City, Edo state,;Nigeria. Electronic address: emmanueljames4uniben@gmail.com.;Medical Student at Dell Medical School, University of Texas at Austin, Texas,;United States. Electronic address: Elkan.gbadebo@utexas.edu.;College of Medicine, University of Nigeria, Nsukka, Enugu state, Nigeria.;Electronic address: Fadeleprecious@gmail.com.;Department of Neurosurgery, Kufa University, Kufa, Iraq. Electronic address:;arwa1999salam@gmail.com.;Department of Public Health and Maritime Transport, University of Thessaly,;Volos, Greece. Electronic address: okesanyaolalekanjohn@gmail.com.;Research Intern, The George Institute for Global Health, India. Electronic;address: vishal.karmani68@gmail.com.;Ambrose Alli University, Ekpoma, Nigeria. Electronic address:;eomomichael@gmail.com.;Department of Global Health and Development, Faculty of Public Health and Policy,;London School of Hygiene and Tropical Medicine, London, United Kingdom; Office;for Research, Innovation and Extension Services, Southern Leyte State University,;Sogod, Southern Leyte, Philippines; Center for University Research, University of;Makati, Makati City, Philippines. Electronic address:;don-eliseo.luceroprisno@lshtm.ac.uk. |
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