| アブストラクト | The spread of antimicrobial-resistant organisms (AROs) poses a major threat to animal and human health. In Japan, the estimated disability-adjusted life years (DALYs) due to infections with AROs is 137.9 per 100,000 persons, with methicillin-resistant Staphylococcus aureus (MRSA) being the main contributor. The factors that can contribute to DALYs in Japan include younger age and a higher number of deaths in patients with MRSA bacteremia. Moreover, longer hospital stays may contribute to higher rates of MRSA bacteremia in Japan than in Western countries. We reviewed diagnosis procedure combination data collected from January 1, 2016, to December 31, 2020, in an acute care hospital in Tokyo, Japan. We found that the median time from admission to MRSA bacteremia onset was 26 days, which is longer than that in Western countries but similar to that in South Korea. Further, our cohort was older than that in the United States and South Korea, potentially contributing to the higher number of years of life lost in Japan. These results underscore the need to develop strategies to reduce hospitalization in Japan. Larger multicenter studies are needed to comprehensively evaluate the economic and health burden of MRSA bacteremia in Japan. |
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| ジャーナル名 | Japanese journal of infectious diseases |
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| 投稿日 | 2024/8/1 |
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| 投稿者 | Okumura, Nobumasa; Tsuzuki, Shinya; Yu, Jiefu; Saito, Sho; Ohmagari, Norio |
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| 組織名 | Disease Control and Prevention Center, National Center for Global Health and;Medicine, Japan.;AMR Clinical Reference Center, National Center for Global Health and Medicine,;Japan.;Faculty of Medicine and Health Sciences, University of Antwerp, Belgium. |
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| Pubmed リンク | https://www.ncbi.nlm.nih.gov/pubmed/39085124/ |
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