| アブストラクト | AIM: To examine treatment patterns of heart failure (HF) in general practice and to evaluate factors influencing the choice of that treatment, such as age, sex, severity of disease and co-morbidity. METHODS: We used previously identified and confirmed incident cases of HF (patients aged 40-84 years) from the General Practice Research Database in the UK (n = 938). We collected recorded information on demographics. co-morbidity and drug treatment prescribed 1 year before and after the incident diagnosis in 1996. RESULTS: Most of the study cohort was over 60 years old and presented with several concomitant diseases. Use of most cardiovascular drugs significantly increased after the diagnosis of HF. There was a greater than threefold increase in the use of angiotensin-converting enzyme inhibitors, while use of nitrates decreased after diagnosis of HF among men. Use of beta-blockers and calcium channel blockers slightly decreased after diagnosis. CONCLUSION: We found that well-established treatment practices were followed by general practitioners. Severity of the disease favoured use of diuretics and a previous ischaemic heart disease and hypertension favoured use of beta-blockers and aspirin. Women and elderly patients were less likely to receive treatment with angiotensin-converting enzyme inhibitors. |
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| ジャーナル名 | European journal of clinical pharmacology |
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| Pubmed追加日 | 2002/3/1 |
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| 投稿者 | Johansson, Saga; Wallander, Mari-Ann; Ruigomez, Ana; Garcia, RodriguezLuisAlberto |
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| 組織名 | Section of Preventive Cardiology, Goteborg University, Sweden. |
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| Pubmed リンク | https://www.ncbi.nlm.nih.gov/pubmed/11868804/ |
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