Unfilled Prescriptions in Japan: A 10-Year Retrospective Analysis.

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Unfilled Prescriptions in Japan: A 10-Year Retrospective Analysis.

Unfilled Prescriptions in Japan: A 10-Year Retrospective Analysis.

アブストラクト	PURPOSE: To describe primary medication non-adherence (PMN; failure to fill newly prescribed medications) patterns in Japan over a decade under universal healthcare coverage. METHODS: We conducted a retrospective cohort study using the DeSC Healthcare database, which integrates pharmacy dispensing records with Japanese medical claims data. We analyzed medical claims with prescription fees from April 2014 to September 2023. PMN was defined as the absence of a pharmacy dispensing record following a documented prescription issuance. RESULTS: We analyzed 2 620 639 medical claims from 1 935 948 unique patients. The overall PMN proportion was 4.9%, with 5.6% in 2014 and 4.3% in 2023. Age-specific subgroup analysis showed proportions ranging from 4.5% to 5.2%. Across all 7 days of the week, proportions ranged from 4.9% to 5.1%. Disease-specific analysis showed proportions ranging from 4.0% (hypertension) to 7.0% (spinal disorders). CONCLUSIONS: PMN remained around 5% over the study period. Health insurers should consider developing notification mechanisms to alert healthcare providers about unfilled prescriptions. Future research should evaluate the impact of electronic prescribing systems.
ジャーナル名	Pharmacoepidemiology and drug safety
Pubmed追加日	2026/1/16
投稿者	Kataoka, Yuki; Tamada, Yudai; Tabuchi, Takahiro; Takeuchi, Kenji
組織名	Center for Postgraduate Clinical Training and Career Development, Nagoya;University Hospital, Nagoya, Japan.;Center for Medical Education, Graduate School of Medicine, Nagoya University,;Nagoya, Japan.;Scientific Research Works Peer Support Group (SRWS-PSG), Osaka, Japan.;Department of Internal Medicine, Kyoto Min-Iren Asukai Hospital, Kyoto, Japan.;Department of Healthcare Epidemiology, Kyoto University Graduate School of;Medicine/School of Public Health, Kyoto, Japan.;Department of International and Community Oral Health, Tohoku University Graduate;School of Dentistry, Sendai, Japan.;Division of Epidemiology, School of Public Health, Graduate School of Medicine,;Tohoku University, Sendai, Japan.;Division of Statistics and Data Science, Liaison Center for Innovative Dentistry,;Tohoku University Graduate School of Dentistry, Sendai, Japan.
Pubmed リンク	https://www.ncbi.nlm.nih.gov/pubmed/41540916/