| アブストラクト | BACKGROUND: Antibiotic use in acne patients has been associated with an increased risk of upper respiratory tract infection (URTI). METHODS: This was a retrospective cohort study using the General Practice Research Database of the United Kingdom. All study subjects were identified as sharing a residence with a patient with a diagnosis of acne. Outcome of interest was a URTI. RESULTS: We identified 98,094 contacts of acne patients. A contact of an acne patient who had a URTI was about 43% more likely to develop a URTI than a contact of an acne patient who did not have a URTI (OR = 1.43 CI = 1.33-1.52, p < 0.001). Exposure to an acne patient using antibiotics did not independently increase a contact's risk of URTI (OR = 0.94, CI = 0.89-1.00, p = 0.063). CONCLUSIONS: Although acne patients on antibiotics are about 2 times more likely to develop URTIs, their household contacts do not appear to be at an increased risk of URTI. |
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| ジャーナル名 | Dermatology (Basel, Switzerland) |
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| Pubmed追加日 | 2007/09/08 |
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| 投稿者 | Bowe, Whitney P; Hoffstad, Ole; Margolis, David J |
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| 組織名 | Department of Dermatology, University of Pennsylvania Center for Education and;Research in Therapeutics, Philadelphia, PA, USA. wpbowe@gmail.com |
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| Pubmed リンク | https://www.ncbi.nlm.nih.gov/pubmed/17823518/ |
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