| アブストラクト | This population-based retrospective cohort study sought to determine if anorexia nervosa (AN) is associated with a higher risk of urolithiasis. Nine thousand three hundred two females with AN were compared to 92 959 randomly selected age-matched and practice-matched females. Cox regression was used to estimate the hazard ratio (HR) for urolithiasis and evaluate effect modification by age. Twenty-three participants with AN (0.25%) developed urolithiasis compared with 154 unexposed participants (0.17%) over a median of 4 years of observation. The risk of urolithiasis varied significantly with age (interaction p = 0.02). AN was associated with a more than threefold higher risk of urolithiasis in females </=25 years of age (HR 3.49, 95% CI: 1.56-7.81; p = 0.002), but not in females over 25 years (HR 1.18, 95% CI: 0.69-2.02; p = 0.54). The distribution of diagnosis codes for urolithiasis differed between groups (p = 0.04), with a higher proportion of codes for uric acid urolithiasis in the AN (16.2%) versus unexposed group (5.0%). Copyright (c) 2017 John Wiley & Sons, Ltd and Eating Disorders Association. |
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| ジャーナル名 | European eating disorders review : the journal of the Eating Disorders Association |
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| Pubmed追加日 | 2017/7/1 |
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| 投稿者 | Denburg, Michelle R; Leonard, Mary B; Jemielita, Thomas O; Golden, Neville H; Tasian, Gregory; Copelovitch, Lawrence |
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| 組織名 | The Children's Hospital of Philadelphia, Perelman School of Medicine at the;University of Pennsylvania, Philadelphia, PA, USA.;Stanford University School of Medicine, Stanford, CA, USA.;Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA,;USA. |
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| Pubmed リンク | https://www.ncbi.nlm.nih.gov/pubmed/28660717/ |
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