| アブストラクト | AIM: To investigate risk factors for first long-bone fractures in children up to 5 years old in order to provide evidence about which families could benefit from injury prevention interventions. METHODS: Population-based matched nested case-control study using The Health Improvement Network, a UK primary care research database, 1988-2004. Maternal, household and child risk factors for injury were assessed among 2456 children with long-bone fractures (cases). 23,661 controls were matched to cases on general practice. Adjusted ORs and 95% CIs were estimated using conditional logistic regression. RESULTS: Fractures of long-bones were independently associated with younger maternal age and higher birth order, with children who were the fourth-born in the family, or later, having a threefold greater odds of fracture compared to first-born children (adjusted OR 3.12, 95% CI 2.08 to 4.68). Children over the age of 1 year had a fourfold (13-24 months, adjusted OR 4.09 95% CI 3.51 to 4.76) to fivefold (37+ months, adjusted OR 4.88 95% CI 4.21 to 5.66) increase in the odds of a long-bone fracture compared to children aged 0-12 months. Children in families with a history of maternal alcohol misuse had a raised odds of long-bone fracture (adjusted OR 2.33, 95% CI 1.13 to 4.82) compared to those with no documented history. CONCLUSIONS: Risk factors for long-bone fractures in children less than 5 years old included age above 1 year, increasing birth order, younger maternal age and maternal alcohol misuse. These risk factors should be used to prioritise families and communities for injury prevention interventions. |
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| ジャーナル名 | Archives of disease in childhood |
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| Pubmed追加日 | 2014/11/16 |
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| 投稿者 | Baker, Ruth; Orton, Elizabeth; Tata, Laila J; Kendrick, Denise |
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| 組織名 | Division of Epidemiology and Public Health, Nottingham City Hospital, University;of Nottingham, Nottingham, UK.;Division of Primary Care, University Park, University of Nottingham, Nottingham,;UK. |
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| Pubmed リンク | https://www.ncbi.nlm.nih.gov/pubmed/25398446/ |
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