| アブストラクト | PURPOSE: To identify practices common to both the General Practice Research Database and The Health Improvement Network database for purposes of combining the databases for analysis without duplicate records. METHODS: We developed two independent algorithms to identify practices common to the two databases. The first used the total number of patients in the therapy and clinical data sets and the total number of etoricoxib and celecoxib users each year during the study period. The second used the total number of patients stratified by gender and four different categories of birth year. Further checking of potential matched practice pairs identified by the two algorithms was performed by comparing the patient-level medical records by birth year, dates of clinical visits, and diagnosis codes. RESULTS: Three hundred twelve potential matched pairs of practices were found by both algorithms. Fifteen additional potential pairs were matched by only one algorithm: 13 by algorithm 1 (A1) only and 2 by algorithm 2 (A2) only. The examination of the patient-level visit dates and diagnosis codes for the matches revealed that all of the 327 potential pairs of duplicate practices were in fact the same practice in the two databases. CONCLUSIONS: The two algorithms successfully found the practices common to the two different databases without de-identifying the practices. The identification of the common practices allows for combining the two databases without duplicate records to create a larger data set for analysis, with 168 more practices than when using the General Practice Research Database alone, or with 268 more practices than when using The Health Improvement Network alone. Copyright (c) 2012 John Wiley & Sons, Ltd. |
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| ジャーナル名 | Pharmacoepidemiology and drug safety |
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| Pubmed追加日 | 2012/5/1 |
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| 投稿者 | Cai, Bing; Xu, Weifeng; Bortnichak, Edward; Watson, Douglas J |
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| 組織名 | Epidemiology, Worldwide Safety Strategy, Pfizer Inc., Collegeville, PA, USA. |
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| Pubmed リンク | https://www.ncbi.nlm.nih.gov/pubmed/22544805/ |
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