| アブストラクト | Aim: To assess the comparative effectiveness of two hypoallergenic formulae in managing cow's milk allergic infants. Materials & methods: This study retrospectively analyzed the case records of 940 formula-fed cow's milk allergic infants in the UK extracted from The Health Improvement Network database. Results: At 24 months after starting a formula, 77% of infants fed an extensively hydrolyzed casein formula supplemented with Lactobacillus rhamnosus GG (eHCF LGG; n = 470) were estimated to have been successfully managed compared with 63% of matched infants who were fed an extensively hydrolyzed whey formula (eHWF; n = 470; p < 0.001). Additionally, significantly more eHWF-fed infants were estimated to be experiencing gastrointestinal symptoms, eczema and asthma (7.1 vs 3.1%; p < 0.02) at 24 months. Conclusion: First-line management of newly diagnosed cow's milk allergic infants with eHCF LGG may slow down the allergic march seen in cow's milk allergic children. |
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| ジャーナル名 | Journal of comparative effectiveness research |
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| 投稿日 | 2019/9/19 |
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| 投稿者 | Guest, Julian F; Fuller, Graham W |
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| 組織名 | Catalyst Consultants, Rickmansworth, UK.;Faculty of Life Sciences & Medicine, King's College, London, UK. |
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| Pubmed リンク | https://www.ncbi.nlm.nih.gov/pubmed/31526139/ |
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