論文・技術情報追加のお知らせ

1. Unraveling Cephalosporin-Associated Anaphylaxis: A Comprehensive Analysis Using FDA Adverse Event Reporting System (FAERS) Data.

FAERSを用いたセフェム系抗生物質に関連するアナフィラキシーの包括的解析

対象DB：FAERS

2. Second Primary Malignancies After Commercial CAR T Cell Therapy: Analysis of FDA Adverse Events Reporting System (FAERS).

CAR T細胞療法後の副作用報告で、536例（4.3%）で2次悪性腫瘍が報告

対象DB：FAERS

3. A real-world pharmacovigilance study of QT interval prolongation and Torsades de Pointes associated with CDK4/6 inhibitors in breast cancer patients: findings from the FDA adverse event reporting system.

CDK4/6阻害剤とQT間隔延長とTorsades de Pointesの関連を評価

対象DB：FAERS

4. Reactive Arthritis After mpox Vaccination.

mpoxワクチン接種後に反応性関節炎が報告された初の症例

対象DB：FAERS,VAERS

5. Streamlining Considerations for Safety Measures: A Predictive Model for Addition of Clinically Significant Adverse Reactions to Japanese Drug Package Inserts.

FAERSとJADERを用いて、重大な有害事象の追加を予測するモデルを構築

対象DB：FAERS,JADER

6. A real-world study of antifibrotic drugs-related adverse events based on the United States food and drug administration adverse event reporting system and VigiAccess databases.

肺線維症治療薬のピルフェニドンとニンテダニブの有害事象と副作用を調査した研究

対象DB：FAERS

7. Reversible cerebral vasoconstriction syndrome and posterior reversible encephalopathy syndrome following vaccination: analysis of the VAERS database and systematic review.

ワクチン接種後のRCVSおよびPRESの包括的な分析

対象DB：FAERS,VAERS

8. Fibrosing colonopathy associated with cysteamine bitartrate delayed-release capsules in cystinosis patients.

システアミン遅延放出製剤に関連する線維性結腸症例を報告

対象DB：FAERS

9. Safety monitoring of bivalent mRNA COVID-19 vaccine among pregnant persons in the vaccine adverse event reporting System - United States, September 1, 2022 - March 31, 2023.

VAERSによる、妊婦におけるバイバレントmRNA COVID-19ワクチン接種の安全性を検討

対象DB：FAERS,VAERS

10. Analysis of drug-induced interstitial lung disease caused by herbal medicine using the Japanese Adverse Drug Event Report database.

ハーブ薬の摂取とDIILDの関連を評価

対象DB：JADER

11. Safety of Biological Therapies for Severe Asthma: An Analysis of Suspected Adverse Reactions Reported in the WHO Pharmacovigilance Database.

VigiBaseを使用した重度喘息バイオロジックの安全性データの概要

対象DB：VigiBase

12. Clinical Features and Outcomes of Shoshin Beriberi.

日本全国のデータを用いて、初期脚気の臨床的特徴を調査

対象DB：DPC

13. Real-world epidemiology and treatment patterns of patients with locally advanced or metastatic urothelial carcinoma: Retrospective analysis of Diagnosis Procedure Combination claims data in Japan.

日本における進行性尿路上皮癌の発生率と治療パターンについての実態調査

対象DB：DPC

14. Postoperative Complications of Surgery for Cervical Spondylotic Myelopathy with and Without Athetoid Cerebral Palsy.

日本の入院患者データを用いた、ACP患者のCSM手術後の合併症と再手術率の調査

対象DB：DPC

15. Association between pharmacotherapy and secondary vertebral fracture managed with a brace in a real-world setting: A nationwide database study in Japan.

薬物療法とSVFの発生率の関連が調査され、薬物服用者は低リスク

対象DB：NDB

16. Cost-effectiveness analysis of minimally invasive surgical treatments for benign prostatic hyperplasia: implications for Japan's public healthcare system.

日本の中等度-重度の前立腺肥大症において、水蒸気エネルギー療法は経尿道的前立腺リフトに比べて、効果的かつ低コスト

対象DB：MDV

17. 5-year mental health outcomes for children and adolescents presenting with psychiatric symptoms to general practitioners in England: a retrospective cohort study.

英国の小児・思春期の精神症状を持つ患者の5年間の診療サービス利用を調査

対象DB：CPRD

18. Effectiveness of Aspirin on Major COPD Outcomes: A Prevalent New-User Design Observational Study.

COPD患者におけるアスピリン使用は全死因死亡率とCOPD急性増悪リスクを増加

対象DB：CPRD

19. Uptake and safety of pneumococcal vaccination in adults with immune mediated inflammatory diseases: a UK wide observational study.

免疫介在性炎症性疾患患者の肺炎球菌ワクチン接種率は低い

対象DB：CPRD

20. The risk of acute infections in new users of antidepressants: An observational cohort study.

抗うつ薬と急性感染の関連は見られず

対象DB：CPRD

21. Sodium-glucose cotransporter-2 inhibitors and the risk of lung cancer among patients with type 2 diabetes.

SGLT-2阻害剤使用と肺癌発生リスクの関連は見られず

対象DB：CPRD

22. Prodromal symptoms of rheumatoid arthritis in a primary care database: variation by ethnicity and socioeconomic status.

関節リウマチの前駆症状は人種や社会経済的地位によって異なる可能性

対象DB：CPRD

23. Within-episode repeat antibiotic prescriptions in patients with respiratory tract infections: a population-based cohort study.

呼吸器感染症での再処方は多いが、同じ抗生物質の再処方は臨床的利益が少ない

対象DB：CPRD

24. How common are side effects of treatment to prevent gout flares when starting allopurinol?

アロプリノール治療開始時の痛風発作予防薬の安全性に関する研究

対象DB：CPRD

25. Risk calculator for incident atrial fibrillation across a range of prediction horizons.

心房細動のリスクが高い個人を予測するモデルの開発

対象DB：CPRD

26. Medication-overuse headache: A pharmacovigilance study in France.

フランスの薬剤副作用データベースに記録された薬物乱用頭痛の副作用報告を分析

対象DB：FPVD