論文・技術情報追加のお知らせ

1. AE-GPT: Using Large Language Models to extract adverse events from surveillance reports-A use case with influenza vaccine adverse events.

VAERSにおける、大規模言語モデルの予防接種の副反応抽出への利用

対象DB：FAERS,VAERS

2. Alpelisib-related adverse events: The FDA Adverse Event Reporting System Database (FAERS) pharmacovigilance study.

アルペリシブの安全性に関するFAERSの解析

対象DB：FAERS

3. Guillain-Barre syndrome and checkpoint inhibitor therapy: insights from pharmacovigilance data.

ICIsとGBSの関連をFAERSで調査

対象DB：FAERS

4. A real-world disproportionality analysis of FDA adverse event reporting system (FAERS) events for alpelisib.

アルペリシブの安全性プロファイルに関する研究

対象DB：FAERS

5. Risk of myocarditis after three doses of COVID-19 mRNA vaccines in the United States, 2020-2022: A self-controlled case series study.

COVID-19ワクチン接種後の心筋炎リスクに関する研究

対象DB：FAERS,VAERS

6. Multidimensional assessment of adverse events of bupropion: A large-scale data analysis from the FAERS database.

ブプロピオンの使用と新たな有害反応

対象DB：FAERS

7. Major adverse cardiovascular events related to phosphodiesterase 5 inhibitors: analysis of real-life data from Eudra-Vigilance database.

PDE5阻害剤の使用と心血管イベントの関連

対象DB：EudraVigilance

8. Modeled Hepatic/Plasma Exposures of Fluvastatin Prescribed Alone in Subjects with Impaired Cytochrome P450 2C9*3 as One of Possible Determinant Factors Likely Associated with Hepatic Toxicity Reported in a Japanese Adverse Event Database.

フルバスタチンの投与量減少と肝・筋肉毒性の関連性

対象DB：JADER

9. Improved Activities of Daily Living With Adjunctive Intravenous Steroids in Bacterial Meningitis: A Nationwide, Population-Based Medical Database Study.

細菌性髄膜炎におけるIVSの活用の有用性の検討

対象DB：DPC

10. A Review of Studies Using Japanese Nationwide Administrative Claims Databases.

日本の4つの行政請求データベースを用いた研究の増加と特徴

対象DB：DPC,NDB

11. Efficacy of initial high- versus low-dose intravenous corticosteroid therapy in patients with acute exacerbation of idiopathic interstitial pneumonia: A nationwide observational study.

AE-IIP患者での高用量と低用量コルチコステロイド療法の比較研究

対象DB：DPC

12. Perioperative outcomes of thyroid cancer surgery in children and adults: a nationwide inpatient database study in Japan.

日本の小児と成人の甲状腺癌手術後の合併症についての比較研究

対象DB：DPC

13. Japanese Multicenter Research of COVID-19 by Assembling Real-world Data: A Study Protocol.

日本におけるCOVID-19後の臨床経過と治療効果の評価のためのデータベース構築

対象DB：DPC

14. The Accuracy of Japanese Administrative Data in Identifying Acute Exacerbation of Idiopathic Pulmonary Fibrosis.

日本の医療データから急性特発性肺線維症の患者を特定する基準を開発

対象DB：DPC

15. Structural and organizational determinants of the capacity for COVID-19 testing and diagnoses in children: Insights from the 2009 influenza and COVID-19 pandemics.

COVID-19の検査と診断能力の要因を調査

対象DB：JMDC

16. Association of white blood cell count after operative vaginal delivery with maternal adverse outcome: A retrospective cohort study.

手術的経膣分娩後の母体の白血球数と感染合併症の関連は不明

対象DB：MDV

17. Androgen deprivation therapy-related fracture risk in prostate cancer: an insurance claims database study in Japan.

日本の前立腺がん患者でのADT使用と骨折リスクの関連の検討

対象DB：MDV

18. Validation Study of Algorithms to Identify Malignant Tumors and Serious Infections in a Japanese Administrative Healthcare Database.

日本の医療データベースでの悪性腫瘍と重篤な感染症の症例検出アルゴリズムの妥当性の検証

対象DB：MDV

19. Concomitant Use of Selective Serotonin Reuptake Inhibitors With Oral Anticoagulants and Risk of Major Bleeding.

SSRIとOACの同時使用は、重大な出血リスクを増加させる

対象DB：CPRD

20. Effectiveness and Safety of Edoxaban Compared With Apixaban in Elderly Patients With Nonvalvular Atrial Fibrillation: A Real-World Population-Based Cohort Study.

高齢者でのエドキサバンとアピキサバンの比較。エドキサバンは出血リスクが高い

対象DB：CPRD

21. Impact of Financial Incentives on Alcohol Consumption Recording in Primary Health Care Among Adults with Schizophrenia and Other Psychoses: A Cross-Sectional and Retrospective Cohort Study.

英国の財政的インセンティブにより、統合失調症患者のアルコールスクリーニングが劇的に増加

対象DB：THIN